As assessed by immunhistochemistry in left ventricle sections after multiple trauma and either DCO or ETC treatment (frame D) diminished C5aR1 staining was identified compared to sham procedure (frame E) whereas complement receptor C5aR2 protein measurement in left ventricular tissue failed to show any differences between sham treated animals and pigs after multiple trauma (frame F). This evidence concerns the gene C5AR1 and Leri-Weill dyschondrosteosis.