Fourteen of the mutated genes in this tumor are involved in metabolism (endogenous molecules as well as drugs), small molecule biochemistry, and cancer: AATF, ATF71P, CRIPAK, CROCC, CYP2A6, DOCK5, GPAT2, KRTAP4–9, LSM14A, MUC2, MYO1F, RHOQ, SUFU, and UTRN (Table 18). This evidence concerns the gene CYP2A6 and cancer.