Patients 2 and 3 both made responses to ribosomal protein S6 kinase, 70 kDa, polypeptide 1 (RPS6KB1), which is overexpressed or amplified in 19% of TCGA lung adenocarcinoma samples (provisional database, as of June 2017) and 10% of squamous cell lung cancer samples (provisional database; as of June 2017). Here, RPS6KB1 is linked to lung adenocarcinoma.