The protoArray data from the current study suggests that CD4 T cells, and hypothetically a coordinated CD8 T cell response, were induced or boosted against a number of proteins whose genes are over-expressed by NSCLC, however, only 1 patient had PBMC and autologous tumor cells available to assess anti-cancer immunity 14 days following their 3rd or 4th vaccination. This evidence concerns the gene CD4 and non-small cell lung carcinoma.