Only splenomegaly and thrombocytopenia did develop in MCMV-infected IFN-γ-KO mice treated with cidofovir on day 0 (data not shown), suggesting that these symptoms may not be linked to viral replication but are rather consequent to the immune response elicited against immediate early and/or early MCMV antigens. Here, IFNG is linked to Splenomegaly.