PRDX2 and colorectal carcinoma: Importantly, the nontargetable PRDX2 rescued the miR-200b-3p-induced repression of CRC cell growth, invasion and metastasis in vivo (Figs. 2g, 3a–c and Additional file 1: Figure S1c, d), suggesting that PRDX2 is sufficient to mediate the effects of miR-200b-3p on regulating biological behaviors of CRC cells in vivo.