PRDX2 and colorectal carcinoma: Importantly, these suppressive effects of miR-200b-3p on malignant behaviors of LoVo cells were substantially weakened by the nontargetable PRDX2 (Fig. 2a, c, e), suggesting that PRDX2 is a functional target of miR-200b-3p in regulating biological behaviors of CRC cells in vitro.