In general, proteins involved in fatty acid β-oxidation such as hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), enoyl-CoA hydratase, short chain, 1, mitochondrial (ECHS1), enoyl-CoA delta isomerase 1 (ECI1) were down- regulated in tumour-bearing animals (p-value < 0.001, Additional file 1). The gene discussed is ECHS1; the disease is neoplasm.