The polymorphism rs174537 is known as an expression quantitative trait locus (eQTL) for the FADS1 and FADS2 genes [22], which encode enzymes involved in the metabolism of polyunsaturated fatty acids and mediate the effects of cyclooxygenase-2 (COX-2) in CRC carcinogenesis. This evidence concerns the gene FADS1 and colorectal carcinoma.