LGALS1 and Miyoshi myopathy: In line with these data, in the first evidence of the role of galectin-1 in MM cells, Abroun et al. reported that galectin-1 binds β1-integrin and supports the proliferation of CD45RA(−) HMCLs, increasing the phosphorylation of ERK, AKT and IkB, and it has an opposite effect on CD45RA(+) MM cells, reducing their proliferation [23] (Figure 1).