Theyinclude gender, alcohol consumption, cigarette smoke, and the intake of CCBs,beta blockers, ACE inhibitors, angiotensin receptor blockers (ARBs, angiotensinII receptor subtype 1 antagonists, sartans), and antilipemics, as well as thediagnosis of arterial hypertension, coronary artery disease (CAD), ventriculararrhythmia, diabetes, acute myocardial infarction (MI), COPD, PH, or pneumonia.Figure 1 shows the distribution ofthese categorical characteristics of the patients with the number of cases foreach parameter. The gene discussed is ACE; the disease is chronic obstructive pulmonary disease.