SOD1 and eye inflammation: Kost et al. reported the preparation of SOD nanozyme by electrostatic coupling of SOD with a cationic block copolymer poly(l-lysine)-poly(ethylene-glycol) and covalent cross-linking with 3,3′-dithiobis (sulfosuccinimidylpropionate), and that the nanozyme was much more effective than the free enzyme in decreasing eye inflammation [6].