For example, Vinod Labhasetwar’s group loaded SOD in poly (d,l-lactide-co-glycolide) NPs using a typical multiple-emulsion solvent-evaporation method, and found that the SOD NPs conferred better protective effects than controls against the oxidative stress of neutron and ischemia-reperfusion injury [3,4]. The gene discussed is SOD1; the disease is ischemia reperfusion injury.