It was found that rats and chicken are resistant to tetanus because VAMP-1 is the predominant isoform in the spinal cord and their VAMP-1 carry the peptide bond Val77-Phe78, not cleavable by TeNT, rather than the TeNT sensitive peptide bond Gln77-Phe78 present in most species, including humans [27]. The gene discussed is VAMP1; the disease is tetanus.