Besides, some screened hub genes were common, like CNN1, an actin filament-associated regulatory protein expressed in smooth muscle and many types of non-muscle cells(Liu and Jin, 2016), and CCDC 34, involved in bladder carcinoma pathogenesis (Gong et al., 2015) and non-small-cell lung cancer (Petroziello et al., 2004). The gene discussed is CNN1; the disease is non-small cell lung carcinoma.