For example, dysregulation of PARK1 and PARK4, associated with some familial forms of PD, are observed in cancers such as adenocarcinoma, lung, colorectal, brain, melanoma, prostate and non-Hodgkin lymphomas (Fung et al., 2003; Matsuo and Kamitani, 2010; Bethge et al., 2014; Li et al., 2015). Here, SNCA is linked to Parkinson disease.