PAX7 and facioscapulohumeral muscular dystrophy: Importantly, PAX7 target gene repression was also found to be a significant biomarker of FSHD status in each of the five microarray FSHD muscle biopsy studies independently, leading to a highly significant repression of PAX7 target genes on meta-analysis (Fisher’s combined test p = 3.5 × 10−9, Fig. 3c).