In a previous study, a decrease in IgE concentrations was found to correlate with an improvement on both asthma control and asthma-related quality of life.27 Furthermore, poor asthma-related quality of life has been shown to be associated with both poor self-rated health and increased sickness behaviour.28 Thus, it could be of interest to investigate the relationship between asthma control and patient-reported outcome measurements in future studies. This evidence concerns the gene IGHE and asthma.