Age, gender, use of aspirin, non-aspirinNSAIDs, 5-areductase inhibitors, statins, angiotensin-II antagonists, oral contraceptives and hormone supplements, antidepressants, antipsychotics, diagnoses of inflammatory bowel disease, COPD, diabetes, alcohol abuse and Charlson Comorbidity Index score. The gene discussed is AGT; the disease is inflammatory bowel disease.