TREM1 and hepatocellular carcinoma: Using a schizophrenia-hepatocellular carcinoma network, the authors found that some schizophrenia candidate genes (SIRPB1, SYK, and LCK) and genes mediating the immune responses in the etiology mechanism of schizophrenia (IL-2 and TREM-1/DAP12) may also function as tumor-suppressor genes [36].