RHOT2 and breast cancer: Also, the expression of OBSCN gene is positively correlated with few other genes such as TOP1MT, MYC, TARPBP1, ADCK3, TRIM17, and RND2. Initially we used metastatic breast cancer data (Metastatic Breast cancer-France 2016) for network analysis and revealed many participating genes such as RHOT2, RAC3, RHOD, ARHGEF7, PAK1, PDPK1, AKT3, RIPK2, ERBB2, PRKD1, etc. which are positively correlated with amplification mutations and have strong association with cell proliferation, differentiation, tumorigenesis and other metastasis features.