CD274 and non-small cell lung carcinoma: A more recent study by Meniawy et al. (2016) found that: a) NSCLC patients have a higher percentage of PD-L1+CD3+ and PD-L1+CD3+CD8+ cells; b) reduced OS is significantly associated (in a univariate analysis) with a high percentage of PD-L1+CD3+ and PD-L1+CD3+CD8+ cells; c) reduced OS is significantly associated (in a multivariate analysis) with a high percentage of PD-L1+CD3+ cells [42].