It is possible that a larger scale study or a different regression model would confirm that, in addition to the predictors previously described, a high percentage of PD-1+CD3+, PD-1+PBMCs, PD-L2+CD3+CD4+ and PD-L2+CD3+CD8+ cells would also be associated with reduced OS in NSCLC patients. The gene discussed is CD8A; the disease is non-small cell lung carcinoma.