For example, prostate cancer patients with prostate volume of 35 cm3 (n = 29) and benign prostatic hyperplasia patients prostate volume of 45 cm3 (n = 35) were measured to have median urinary PSA levels of 52.6 ng/mL and 123.2 ng/mL, respectively [28]. This evidence concerns the gene KLK3 and Familial prostate cancer.