The quantitation of cleaved caspase 3 stains across the control and treatment group shows a statistically significant increase in the percentage of CC3 positive cells in AXT050 treated tumor sections compared to controls (Mean ± SEM of control= 31.10 ± 0.2982, n=20 vs Mean ± SEM of AXT050= 44.60 ± 0.5956, n=20, p< 0.0001) (Figure 4F). Here, CASP3 is linked to neoplasm.