Finally, we conducted a logistic regression analysis with disease status (breast cancer vs healthy status) as dependent variable demonstrating that Leptin serum level (OR 0.23; 95% CI:0.06–0.76; p < 0.01) and age (OR 0.05; 95% CI:0.05–0.61 p < 0.007) were the only factors significantly retained in the final model while BRCA status, Adiponectin and Ghrelin did not (Table 3). This evidence concerns the gene LEP and breast cancer.