Logistic regression analysis demonstrated that Adiponectin plasma level (OR 0.26; 95% CI:0.007–0.81; p < 0.02) and age (OR 5.51; 95% CI:1.78–19.71; p < 0.004) were the only factors independently associated with BMI; furthermore, Leptin plasma level (OR 0.23; 95% CI:0.06–0.76; p < 0.01) and age (OR 0.05; 95% CI:0.05–0.61; p < 0.007) resulted the only factors significantly associated with breast cancer. The gene discussed is ADIPOQ; the disease is breast cancer.