Based on the results of the eIF basic characterization in CRC patients (Figure 3, Figure 4, Supplementary Figure 11 and Supplementary Figure 12), eIF1, eIF5 and eIF6 were identified as novel factors, which are significantly activated in CRC (Supplementary Tables 1 and 2) and might therefore represent potential targets for future therapeutic intervention. Here, EIF5 is linked to colorectal carcinoma.