GPC1 is involved in tumor growth and angiogenesis [7–9] through the activation of FGF-FGFR signaling [13] and GPC1 expression can be suppressed by miR-96-5p in pancreatic cancer cells [14] or regulated by miRNA-149 in human endothelial cells [15]. This evidence concerns the gene GPC1 and pancreatic neoplasm.