Of the transcripts annotated as “TGFβ signaling pathway” and reported as regulators of EMT, we focused on 12 genes (BMP6, BTG2, CD2AP, EPHA4, EZH1, LTBP1, MXD1, NEO1, PDCD4, RFFL, SDC4 and TIMP3) for further analysis according to their known functions in cancers [13, 16–26]. The gene discussed is RFFL; the disease is cancer.