KHSRP and esophageal squamous cell carcinoma: In KHSRP-overexpressing ESCC cells, inhibition of each of the endogenously expressed target miRNAs released the up-regulation of the corresponding targets at both mRNA and protein expression levels, and inhibited cell migration/invasion (Figures 5A–5D), whereas introduction of each of the miRNA mimics into KHSRP-knockdown cells inhibited expression levels of the corresponding target proteins and restored cell migration, at least partly.