In this study, we observed high basal levels of p-STAT3 and altered expression of apoptotic proteins such as tumor protein 53 (p53), B-cell lymphoma-2 (Bcl-2), Bcl-2 associated X protein (Bax) and cleaved poly (ADP-ribosyl) polymerase (PARP) in gastric cancer cells (SGC-7901) as expected. This evidence concerns the gene STAT3 and gastric cancer.