RRAD and neoplasm: To examine whether dual immune checkpoint blockade or combination therapy is effective in inhibiting metastasis, we assessed the number of metastatic nodules in lungs, kidneys and liver in mice in the No Tx (N = 8), P1C4 (N = 6), RAD (N = 5), and COMB (N = 5) groups on day 31 after tumor inoculation.