Based on data from a previous study (10), cytokines (IL-6, IL-12p70), chemokines (CCL2/MCP-1, CCL4/MIP-1β, CCL5/RANTES, CCL11/Eotaxin), and regulatory molecules (IL-1RA, sIL-2R) with differential serum concentrations in patients with CNO as compared to Crohn’s disease or JIA, and healthy individuals were included. The gene discussed is CCL4; the disease is juvenile idiopathic arthritis.