However, when the IgA results were coordinated with ESAT-6 or CFP-10 specific IFN-γ releasing levels (Supplementary Figure 2), the diagnostic sensitivities of the ESAT-6 and CFP-10-specific IFN-γ release assays for TB patients were substantially improved from 86.11 to 100% and 88.89 to 100%, respectively, and the specificities remained at 72.12 and 72.12% (Table 3). Here, IFNG is linked to tuberculosis.