Taken together these data suggest that human primary OECs display significant increases in the expression of MMPs and Vimentin which are largely associated with metastatic potential in cancers (Kessenbrock et al., 2010; Liu et al., 2010; Satelli and Li, 2011; Kidd et al., 2014; Basu et al., 2015) and promote a migratory phenotype in the host cells during extended period of infection by P. gingival is (Figure 8). Here, VIM is linked to infection.