A very interesting study on tumorigenesis of Hodgkin's lymphoma provided evidence that endogenous LTR activation can be oncogenic and hypomethylation of the THE1B LTR (a MaLR family LTR retrotransposon, the same family THE1 with THE1C-int found in our study) caused the CSF1R (colony stimulating factor 1 receptor gene) oncogene activation. Here, CSF1R is linked to Hodgkins lymphoma.