The CD11c+ mDC expressed indoleamine-2,3-dioxygenase (IDO, a regulator of T cell development), VEGF and IL4 (immune tolerance cytokines), as well as IL6 and IL23a (pro-inflammatory cytokines that can be involved in Th17 phenotype skewing) but not TGFβ1 or IL10 (frequently involved in anti-tumor immune responses). The gene discussed is TGFB1; the disease is neoplasm.