Many studies have examined the associations between MMP-2-1306 C/T (rs243865) and MMP-1-1607 1G/2G (rs1799750) polymorphisms and risk of prostate cancer (Yaykasli et al., 2014; Adabi et al., 2015; Shajarehpoor Salavati et al., 2017). This evidence concerns the gene MMP2 and Familial prostate cancer.