OR51E2 and Familial prostate cancer: The few studies investigating their function show that the activation of human ORs leads to, for example, secretion processes or influences the cell proliferation such as OR51E2 in prostate cancer cells or in melanocytes (Spehr et al., 2003; Braun et al., 2007; Neuhaus et al., 2009; Veitinger et al., 2011; Sanz et al., 2014; Kang et al., 2015; Kim et al., 2015; Gelis et al., 2016; Kalbe et al., 2016b; Manteniotis et al., 2016b; Tsai et al., 2017; Weber et al., 2017).