GPT and metabolic dysfunction-associated steatotic liver disease: Before adulthood, the juvenile mice manifested the characteristics of NAFLD, ranging from liver dysfunction (ALT > AST), elevated liver TG and TC contents, and IR to distinct liver histological pattern, with the predominant damage in the portal area: increased portal inflammation and fibrosis (Schwimmer et al., 2005; Carter-Kent et al., 2009; Fleet et al., 2017).