Although associations with APC, KRAS, and CIN have not been directly considered, the fact that BMI and waist measurements are positively associated with BRAF mutations and BRAF-wildtype, MSI and microsatellite stable tumors, and CIMP-H and non-CIMP tumors, is in accordance with WCRF evidence showing that overweight is a strong risk factor for CRC in general. The gene discussed is KRAS; the disease is colorectal carcinoma.