Two subsets of MDSCs were recently defined: monocytic MDSCs, which express CD11b+Ly6ChighLy6G−, and granulocytic MDSCs, which express CD11b+Ly6G+Ly6Clow; each population has a different function in cancer, parasitic infections, and autoimmunity [26, 27]. The gene discussed is ITGAM; the disease is cancer.