IL18 and infection: Pathway enrichment analysis revealed a significant and positive correlation of NKT cells (normalized enrichment score [NES] = 1.48, false discovery rate [FDR] = 0.06), IL-4 (NES = 1.43, FDR = 0.02), IL-18 (NES = 1.42, FDR = 0.05), and STAT6 signaling (NES = 1.83, FDR = 0.02) signatures as early as day 3 of infection with neutralizing antibody titers at day 7 (Figure 7J).