Being obese at the end of cALL treatment was significantly associated with the presence of obesity at interview (RR: 2.17, 95% CI: 1.47–3.21) and metabolic syndrome – IDF definition (RR: 3.23, 95% CI: 1.28–8.14) (Table 3). This evidence concerns the gene CHL1 and obesity due to melanocortin 4 receptor deficiency.