Hoster et al. reported that significant differences in time to treatment failure (64 months versus 19 months) and overall survival (OS) (not reached versus 45 months) were found between the Ki-67 level < 30% group versus the Ki-67 level ≥ 30% group in 543 MCL cases (p < 0.0001 each) [12]. Here, MKI67 is linked to mantle cell lymphoma.