As shown in Fig. 6, serum levels of GOT (Fig. 7a) and GPT (Fig. 7b) as liver toxic markers were increased in the LT4-induced hyperthyroidism group, but these increases were significantly decreased by the treatment of MOK pharmacopuncture at 0.3, and 3 mg/kg similar to the PTU-treated group. Here, GPT is linked to hyperthyroidism.