Time of measurement, cutoff point and diagnostic accuracy of urinary [TIMP-2] × [IGFBP7] in each individual study for AKI diagnosis, including true positive (TP), true negative (TN), false positive (FP) and false negative (FN), sensitivity, specificity and the area under the summary receiver operating characteristic (AUROC) values are listed in Table 2. This evidence concerns the gene IGFBP7 and acute kidney injury.