In the included studies of this meta-analysis, the outcomes were represented as tumor weight, tumor volume, or both; diverse lncRNA types (HOTAIR, MALAT1, PVT1,TUG1, and so on) or functions (oncogenes or tumor suppressors) were reported; various osteosarcoma cell lines were used to produce osteosarcoma xenograft models (MG-63, U2 OS or MNNG/HOS cells) and different methods were used to produce xenograft models (subcutaneous inoculation or peritoneal metastasis) (Table 1). The gene discussed is HOTAIR; the disease is osteosarcoma.