As shown in Figure 2B, the enhanced reporter activities of IFIT1 and IFIT2 by β-catenin siRNA#12 were suppressed in part by the expression of β-catenin, supporting that β-catenin play a suppressive role in the transcriptional activities of IFIT1 and IFIT2 in CRC cells. This evidence concerns the gene IFIT2 and colorectal carcinoma.