To investigate that if miRNAs are involved in increased P3 mRNA expression in HCC, we predicted candidate miRNAs targeting the P3 mRNA 5′UTR (NM_000612) only, that is to say, they do not bind to the 3′UTR and 5′UTR of the other three transcrips, P1-P4 promoters, and IGF-II protein coding region of IGF-II gene using RegRNA (http://regrna.mbc.nctu. Here, IGF2 is linked to hepatocellular carcinoma.