We then infected MSCs with these selected lentivirus expressed shRNAs after confirming the successful knockdown of GARP expression on the shRNA-infected MSCs 96 h post infection,, we compared their efficacy of inhibiting the proliferation of activated T cells and IFN-γ production from the activated T cells with MSCs infected with the same number of control empty lentivirus particles at the same time. This evidence concerns the gene IFNG and infection.