NLRP3 and cardiomyopathy: Our results demonstrate that the NLRP3 deficient mice are protected from HSD, HFD and HSFD-associated body-weight gain, left ventricle hypertrophy and increased myocardial mass and related cardiomyopathies, and the disappearance of different cardiac remodeling-related dysfunctions and the absence of alterations in key biochemical biomarkers.