In oral tongue squamous cell carcinoma, PCLP1 induces chemoresistance to cisplatin through a mechanism involving B-cell-specific lymphoma Moloney murine leukemia virus integration site 1 homolog (BMI-1) [12], an oncogene that collaborates with MYC in the development of murine lymphoma [51] and which causes drug resistance in B-cell lymphoma cells [52]. Here, BMI1 is linked to B-cell non-Hodgkin lymphoma.