AQP1 and astrocytoma (excluding glioblastoma): As shown in Table 6 and Table 7, both univariate and multivariate Cox proportional hazard regression analysis demonstrated that combination of AQP1 and β-catenin expression was an independent factor for astrocytoma (OS: P = 0.048; PFS: P = 0.015) independent of age, tumor size and histological grade.