NTRK2 and neoplasm: However, the expression of TrkB was positively associated with large tumor size (OR: 1.96, 95% CI: 1.47–2.61), lymph node metastasis (OR: 1.93, 95% CI: 1.50–2.48), distant metastasis (OR: 2.76, 95% CI: 1.78–4.26) and a higher clinical stage (OR: 1.78, 95% CI: 1.16–2.72) in the fixed-effects model without significant heterogeneities (see Table 3).